OUR TECHNOLOGY

A Site-Specific Genome
Engineering Platform

A non-viral, programmable platform to stably and safely integrate large, multi-gene programs into iPSCs for next-generation cell therapies.

Luminous DNA helix

How Our Technology Works

Engineered iPSC cells

iPSCs

Chromosome with a landing pad at a defined siteLANDING PAD

Engineer iPSCs with a landing pad at a proprietary safe harbor site

Integrate a large, multi-gene cassette into the landing pad

Engineered iPSC cells

Engineered iPSCs

(with integrated multi-gene program)

Key Advantages

Site-specific and predictable integration

Integration of
large multigenic cargo

Non-viral approach with no double-strand breaks

Long-term expression in stem cells with no cytotoxicity