:root {
  color-scheme: light;
  --navy: #09143d;
  --blue: #0878ec;
  --deep-blue: #034bba;
  --text: #0b1743;
  --muted: #10245b;
  font-family: "DM Sans", Arial, sans-serif;
}

* { box-sizing: border-box; }
html { scroll-behavior: smooth; }
body {
  margin: 0;
  color: var(--text);
  background:
    radial-gradient(ellipse at 0% 34%, rgba(208, 235, 255, .56), transparent 23rem),
    radial-gradient(ellipse at 100% 30%, rgba(206, 235, 255, .46), transparent 22rem),
    #fff;
}
a { color: inherit; text-decoration: none; }
.site-header {
  width: min(100% - 48px, 1140px);
  height: 76px;
  margin: 0 auto;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 24px;
}
.brand { display: flex; align-items: center; flex: 0 0 auto; }
.brand img { display: block; width: 272px; height: 50px; object-fit: contain; mix-blend-mode: multiply; }
.brand-home .brand-lockup { display: block; width: 272px; }
.brand-home .brand-wordmark { display: block; height: 35px; overflow: hidden; }
.brand-home .brand-wordmark img { width: 100%; height: auto; }
.brand-home .brand-tagline { display: block; margin: 3px 0 0 54px; color: #16356e; font-family: Arial, sans-serif; font-size: 7.6px; line-height: 1.2; font-weight: 700; letter-spacing: .01em; text-transform: uppercase; white-space: nowrap; }
.brand-mark { color: #13245a; font-size: 28px; letter-spacing: -9px; transform: scaleX(1.1); padding-right: 6px; }
.brand-copy { display: flex; flex-direction: column; line-height: 1; }
.brand-name { font-size: 28px; font-weight: 800; letter-spacing: -1.7px; color: #101735; }
.brand-name span { color: #1477e9; }
.brand-copy small { margin-top: 5px; font-size: 7px; letter-spacing: .03em; color: #273d78; font-weight: 700; }
.main-nav { display: flex; align-items: center; gap: clamp(18px, 3vw, 44px); font-size: 15px; font-weight: 600; white-space: nowrap; }
.main-nav a { position: relative; padding: 8px 0; }
.main-nav a.active { color: #004cc3; }
.main-nav a.active::after { content: ""; position: absolute; left: 0; right: 0; bottom: 2px; height: 2px; background: #0878ec; }
.contact-button { padding: 13px 27px; border-radius: 999px; color: white; background: #0756bd; font-size: 14px; font-weight: 700; white-space: nowrap; box-shadow: 0 5px 14px rgba(7, 86, 189, .12); }
.hero { width: min(100% - 48px, 1140px); margin: 34px auto 0; text-align: center; }
.eyebrow { margin: 0 0 19px; color: #075fdb; font-size: 12px; letter-spacing: .39em; font-weight: 800; }
h1 { margin: 0; color: #090e27; font-size: clamp(34px, 4.4vw, 53px); line-height: 1.12; letter-spacing: -.045em; font-weight: 800; }
h1 span { color: #0c80ef; }
.hero-lede { margin: 13px 0 25px; color: #0a2d86; font-size: clamp(17px, 2vw, 22px); line-height: 1.4; letter-spacing: -.025em; }
.process { display: grid; grid-template-columns: 1fr 34px 1.28fr 34px 1fr 34px 1.25fr 34px .82fr; align-items: center; gap: 0; }
.process-step { min-width: 0; text-align: center; }
.process-art { height: clamp(128px, 14vw, 168px); display: flex; justify-content: center; align-items: center; }
.process-art img { display: block; width: 100%; height: 100%; object-fit: contain; }
.process-step h2 { margin: 4px 0 2px; color: #080f2e; font-size: 17px; line-height: 1.15; font-weight: 800; letter-spacing: -.04em; }
.process-step p { margin: 0; color: #0d2874; font-size: 15px; line-height: 1.3; letter-spacing: -.025em; }
.patient-step .process-art img { max-width: 86px; }
.flow-arrow { display: block; width: 100%; height: 3px; background: linear-gradient(90deg, #c8e7ff, #1782ec); position: relative; margin-top: -38px; }
.flow-arrow::after { content: ""; position: absolute; right: -1px; top: -5px; border-top: 6px solid transparent; border-bottom: 6px solid transparent; border-left: 9px solid #1782ec; }
.platform-rule { display: flex; align-items: center; justify-content: center; gap: 18px; margin: 39px auto 38px; color: #0760d8; font-size: 12px; letter-spacing: .36em; font-weight: 800; }
.platform-rule span { width: min(24%, 275px); height: 1px; background: #175ad0; }
.pathways { width: min(100% - 48px, 1140px); margin: 0 auto; display: grid; grid-template-columns: repeat(5, minmax(0, 1fr)); gap: 12px; }
.pathway-card { min-height: 380px; border-radius: 12px; padding: 15px 18px 18px; display: flex; flex-direction: column; align-items: center; text-align: center; color: #09143d; }
.technology-card { background: linear-gradient(145deg, #f6efff, #f2edff); }
.immunotherapy-card { background: linear-gradient(145deg, #e8f5ff, #e9f4ff); }
.cell-lines-card { background: linear-gradient(145deg, #efffed, #effbed); }
.company-card { background: linear-gradient(145deg, #fff8eb, #fff5e5); }
.partners-card { background: linear-gradient(145deg, #e9f8f8, #e2f5f3); }
.card-icon { display: block; height: 88px; width: 122px; object-fit: contain; margin: 0 auto 4px; }
.pathway-card h2 { min-height: 43px; display: flex; justify-content: center; align-items: center; margin: 0 0 7px; font-size: 19px; line-height: 1.12; font-weight: 800; letter-spacing: -.05em; }
.pathway-card p { margin: 0 0 11px; font-size: 15px; line-height: 1.3; letter-spacing: -.025em; }
.pathway-card ul { width: 100%; margin: 8px 0 16px; padding-left: 17px; text-align: left; font-size: 14px; line-height: 1.27; }
.pathway-card li { padding-left: 2px; margin-bottom: 5px; }
.pathway-card a { display: block; margin-top: auto; color: #6720e8; font-size: 15px; line-height: 1.2; font-weight: 800; letter-spacing: -.04em; }
.pathway-card a span { font-size: 20px; vertical-align: -1px; }
.immunotherapy-card a { color: #0664d8; white-space: nowrap; font-size: 14px; }
.cell-lines-card a { color: #16812c; }
.company-card a { color: #c77a00; }
.partners-card a { color: #08777b; }
.immunotherapy-card p:nth-of-type(2) { margin-top: 0; }
.pathway-card .collab { color: #056be3; font-size: 12px; line-height: 1.15; font-style: italic; font-weight: 600; margin: auto 0 12px; }
.site-footer { min-height: 154px; margin-top: 21px; padding: 18px 24px 30px; text-align: center; position: relative; overflow: hidden; background: radial-gradient(ellipse at 98% 100%, rgba(175, 224, 255, .7), transparent 34%), radial-gradient(ellipse at 90% 110%, rgba(219, 242, 255, .85), transparent 45%); }
.site-footer::after { content: ""; position: absolute; right: -5%; bottom: -50px; width: 45%; height: 115px; border-radius: 50% 50% 0 0; background: linear-gradient(155deg, rgba(218, 241, 255, .12), rgba(174, 224, 255, .55)); transform: rotate(-9deg); pointer-events: none; }
.footer-tagline { position: relative; z-index: 1; margin: 2px 0 12px; color: #12266f; font-family: "Playfair Display", Georgia, serif; font-size: 20px; font-style: italic; }
.footer-brand { position: relative; z-index: 1; display: flex; align-items: center; justify-content: center; gap: 17px; color: #1477e9; font-size: 20px; }
.footer-brand > span { display: block; width: 58px; height: 1px; background: #1644b6; }
.footer-brand b { letter-spacing: -.05em; }
.footer-brand b span { color: #7925e8; }
.footer-words { position: absolute; z-index: 1; right: max(30px, calc((100% - 1090px) / 2)); bottom: 13px; color: #0e3a9c; font-size: 10px; font-weight: 800; letter-spacing: .38em; }
.footer-words i { margin: 0 13px; font-style: normal; }

@media (max-width: 980px) {
  .site-header { width: min(100% - 32px, 820px); height: auto; min-height: 72px; flex-wrap: wrap; padding: 12px 0; }
  .main-nav { order: 3; width: 100%; justify-content: center; gap: 24px; overflow-x: auto; font-size: 13px; }
  .hero, .pathways { width: min(100% - 32px, 820px); }
  .process { grid-template-columns: repeat(5, 1fr); gap: 10px; }
  .flow-arrow { display: none; }
  .process-art { height: 135px; }
  .process-step h2 { font-size: 15px; }
  .process-step p { font-size: 13px; }
  .pathways { grid-template-columns: repeat(3, minmax(0, 1fr)); }
}
@media (max-width: 620px) {
  .site-header { width: calc(100% - 28px); gap: 12px; }
  .brand img { width: min(230px, 58vw); height: 42px; }
  .brand-home .brand-lockup { width: min(230px, 58vw); }
  .brand-home .brand-wordmark { height: min(29px, 7.4vw); }
  .brand-home .brand-tagline { margin-left: 19.85%; font-size: min(6.4px, 1.62vw); }
  .contact-button { padding: 10px 15px; font-size: 12px; }
  .main-nav { justify-content: flex-start; gap: 22px; }
  .hero { width: calc(100% - 30px); margin-top: 28px; }
  .eyebrow { font-size: 9px; letter-spacing: .28em; }
  h1 { font-size: clamp(31px, 9vw, 43px); }
  h1 br { display: none; }
  .hero-lede { font-size: 16px; }
  .desktop-break { display: none; }
  .process { grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 20px 12px; }
  .process-step:last-child { grid-column: 1 / -1; }
  .process-art { height: 132px; }
  .process-step h2 { font-size: 15px; }
  .process-step p { font-size: 13px; }
  .platform-rule { gap: 9px; margin: 30px auto; font-size: 8px; letter-spacing: .2em; }
  .platform-rule span { width: 13%; }
  .pathways { width: calc(100% - 28px); grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 10px; }
  .pathway-card { min-height: 360px; padding: 14px 12px 16px; }
  .pathway-card h2 { font-size: 17px; }
  .pathway-card p { font-size: 13px; }
  .pathway-card ul { font-size: 12px; }
  .pathway-card a { font-size: 13px; }
  .card-icon { height: 76px; width: 110px; }
  .site-footer { margin-top: 16px; }
  .footer-tagline { font-size: 16px; }
  .footer-words { position: relative; right: auto; bottom: auto; margin-top: 22px; font-size: 8px; }
}